Researching alveoli

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Cell surface RNA expression modulates alveolar epithelial function

Jubilant Kwame Abledu, Christopher J. Herbst, Raphael Brandt, Alen Kocak, Pritam Ghosh, Jacob L. Gorenflos López, Kevin Diestelhorst, Stephan Block, Christian Hackenberger, Oliver Seitz, Elena Lopez-Rodriguez, Cengiz Gökeri, Martin Witzenrath, Matthias Ochs, and Wolfgang M Kuebler. Am J Resp Cell Mol Biol 2025: in press. To access the full article,

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Comparative electron microscopic visualization of the lung alveolar epithelial glycocalyx with different staining and labeling methods

Vladimir Gluhovic, Sara Timm, Wolfgang M. Kuebler, Elena Lopez-Rodriguez, Matthias Ochs. Journal of Anatomy, 2024: 00, 1–12 To access the full article, click here: The alveolar surface of the lung is lined by an epithelium consisting of type I (AECI) and type II alveolar epithelial cells (AECII). This epithelium

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Multivalent, calcium-independent binding of surfactant protein A and D to sulfated glycosaminoglycans of the alveolar epithelial glycocalyx

SP-A and SP-D function has been related to innate immunity of the lung based on their binding to sugar residues at pathogen surfaces. Here, we demonstrated that these proteins bind to glycosaminoglycans present at typical cell surfaces like the alveolar epithelial glycocalyx.

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