Open Access

Giambelluca, S., Ochs, M., Lopez-Rodriguez, E.: Front Immunol. 2022;13:958098. To access the full article, click here: Background: The activation of NLRP3 inflammasome in macrophages has been proven to play a crucial role in the development of cardiovascular diseases. THP-1 monocytes can be differentiated to macrophages by incubation with

Hoffmann, K., Obermayer, B., Hönzke, K., Fatykhova, D., Demir, Z., Löwa, A., Alves, L.G.T., Wyler, E., Lopez-Rodriguez, E., Mieth, M., Baumgardt, M., Hoppe, J., Firsching, T.C., Tönnies, M., Bauer, T.T., Eggeling, S., Tran, H.L., Schneider, P., Neudecker, J., Rückert, J.C., Gruber, A.D., Ochs,

Lettau, M., Timm, S., Dittmayer, C., Lopez-Rodriguez, E., Ochs, M.: Am J Physiol-Lung C. 2022;322(6):L873-81. To access the full article, click here: Weibel’s hypothetical three-dimensional (3-D) model in 1966 provided first ultrastructural details into tubular myelin (TM), a unique, complex surfactant subtype found in the hypophase

Brinkert, K., Hedtfeld, S., Burhop, A., Gastmeier, R., Gad, P., Wedekind, D., Kloth, C., Rothschuh, J., Lachmann, N., Hetzel, M., Jirmo, A.C., Lopez-Rodriguez, E., Brandenberger, C., Hansen, G., Schambach, A., Ackermann, M., Tümmler, B., Munder, A.: Mol Ther. 2021;29(3):1324-34. To access the full article, click here:

Krischer, J.M., Albert, K., Pfaffenroth, A., Lopez-Rodriguez, E., Ruppert, C., Smith, B.J., Knudsen, L.: Histochem Cell Biol. 2021;155(2):183-202. To access the full article, click here: Mechanical ventilation triggers the manifestation of lung injury and pre-injured lungs are more susceptible. Ventilation-induced abnormalities of alveolar surfactant are

Testoni, G., Olmeda, B., Duran, J., Lopez-Rodriguez, E., Aguilera, M., Hernández-Álvarez, M.I., Prats, N., Pérez-Gil, J., Guinovart, J.J.: Hum Mol Genet. 2021;29(21):3554-65. To access the full article, click here: The glycogenin knockout mouse is a model of Glycogen Storage Disease type XV. These animals show

Lopez-Rodriguez, E., Gay-Jordi, G., Knudsen, L., Ochs, M., Serrano-Mollar, A.: Front Med. 2021;8:640020. To access the full article, click here: Idiopathic pulmonary fibrosis (IPF) is a progressively and ultimately fatal lung disease. Previously it has been shown that intratracheal administration of alveolar epithelial type II cells (AE2C) in

Brandt, R., Timm, S., Gorenflos López, J.L., Kwame Abledu, J., Kuebler, W.M., Hackenberger, C.P.R., Ochs, M., Lopez-Rodriguez, E.: Front Bioeng Biotech. 2021;8:614357. To access the full article, click here: The glycocalyx—a plethora of sugars forming a dense layer that covers the cell membrane—

Albert, K., Krischer, J.M., Pfaffenroth, A., Wilde, S., Lopez-Rodriguez, E., Braun, A., Smith, B.J., Knudsen, L.: Front Physiol. 2020;11:530485. To access the full article, click here: Mechanical ventilation of lungs suffering from microatelectases may trigger the development of acute lung injury (ALI). Direct lung injury by